Linked-read Sequencing

Linked-read Sequencing

        10x Genomics Chromium System全新資料型式大幅提升您次代定序的品質。相較於次代定序傳統短片段訊息較難完整組裝全基因體資訊,Chromium System將短片段訊息利用目錄化方式整合成為更有效率的解讀型式。不論是全基因體定序(Whole Genome Sequencing)、全外顯子定序(Whole Exome Sequencing)、基因體創始建構(De Novo Assembly)、基因體結構變異(Genome Structural Variant)等等,Chromium System協助您更深入且更精準的探索基因體學的奧妙。

 

Figure 1. Chromium System links reads in difficult regions that share a barcode with those in flanking confident regions to anchor them.

 

Table 1. Summary of Variant Classes Called and Phased Using the Chromium™ Genome Solution.

 

Table 2. Supernova Assembler on four human samples and five non-human samples